What are the side effects of antiepileptic drugs?
In addition to the common side effects of antiepileptic drugs, like dizziness, drowsiness, and mental slowing; other side effects like weight gain, metabolic acidosis, nephrolithiasis, angle closure glaucoma, skin rash, hepatotoxicity, colitis, and movement and behavioral disorders, to name a few, have been brought to …
What is the mechanism of action of phenytoin?
Phenytoin is often described as a non-specific sodium channel blocker and targets almost all voltage-gated sodium channel subtypes. More specifically, phenytoin prevents seizures by inhibiting the positive feedback loop that results in neuronal propagation of high frequency action potentials.
What is the difference between anticonvulsant drugs and antiepileptic drugs?
Antiepileptic and anticonvulsant are both terms that refer to the same drugs that target different neural pathways to reduce seizure episodes in people with epilepsy disorders. Anticonvulsants are another name for antiepileptic drugs, which are medications used to treat seizure disorders and help suppress seizures.
What’s the best medication for epilepsy?
Many medications are used in the treatment of epilepsy and seizures, including:
- Carbamazepine (Carbatrol, Tegretol, others)
- Phenytoin (Dilantin, Phenytek)
- Valproic acid (Depakene)
- Oxcarbazepine (Oxtellar, Trileptal)
- Lamotrigine (Lamictal)
- Gabapentin (Gralise, Neurontin)
- Topiramate (Topamax)
What is the best seizure medicine?
What is the mechanism of action of clobazam?
The mechanism of action for clobazam is not fully understood but is thought to involve what is known as potentiation of GABAergic neurotransmission resulting from binding at a benzodiazepine site at the GABA(A) receptor.
Which is the mechanism of action of antiepileptic drugs?
Succinic. Semialdehyde. Gabapentin. GT: GABA transaminase. SSD:Succinic semialdehyde dehydrogenase. GT. SSD. Vigabatrin. Valproate. Benzodiazepines – PowerPoint PPT presentation PowerShow.com is a leading presentation/slideshow sharing website.
Are there any antiepileptic drugs on SlideShare?
What are the mechanisms of action of Addi-tion?
In addi- tion, many of the newer AEDs also have unique mechanisms of action compared with previously available agents. First-generation AEDs are pro- posed to have a couple of primary mechanisms of action. Sodium channel blockade and GABA potentiation both result in a reduction of neu- ronal discharge.
When to start an anti epileptic drug treatment?
GENERAL PRINCIPLES FOR TREATMENT OF EPILEPSY GENERAL PRINCIPLES FOR TREATMENT OF EPILEPSY : : 1. One fit is an indication for investigation but not for treatment. 2 . Treatment should be started after second seizure. 3 . Once drug treatment is started it should be continued until the patient has been free of fits for 2 – 3 years. 4 .