Can HSP cause nephrotic syndrome?

Can HSP cause nephrotic syndrome?

Glomerulonephritis (HSPN) occurs in 30-50 % of HSP patients, mostly in a mild form but a small percentage of patients present with nephrotic syndrome or renal failure.

Is HSP nephrotic or nephritic?

Henoch-Schönlein purpura nephritis is a rare kidney disease leading to chronic kidney disease in a non-negligible percentage of patients. Although retrospective studies suggest beneficial effects of some therapies, prospective randomized clinical trials proving treatment efficacy are still lacking.

What causes HSP nephritis?

HSP is an autoimmune disorder. This is when the body’s immune system attacks the body’s own cells and organs. With HSP, this immune response may be caused by an upper respiratory tract infection. Other immune triggers may include an allergic reaction, medicine, injury, or being out in cold weather.

Can HSP cause kidney damage?

There is no medicine to treat HSP, and treatments for the disease involve treating the symptoms, like the swelling, stomach pain, and arthritis. Most people recover fully from HSP without complications, but it can lead to chronic kidney disease and kidney failure over time.

How long can HSP last?

How long does Henoch-Schonlein purpura last? The illness lasts 4 to 6 weeks in most patients. The rash (purpura) changes from red to purple, becomes rust-coloured and then fades completely. About 3 in 10 of those with HSP can get it again, usually within 4 months of the initial illness.

Can HSP be misdiagnosed?

HSP may be misdiagnosed as another form of vasculitis – most commonly hypersensitivity vasculitis – because of the frequent failure to perform direct immunofluorescence (DIF) testing on skin biopsy and the consequent failure to detect IgA.

Can HSP come back years later?

About one third of children diagnosed with Henoch-Schönlein purpura will develop recurrent symptoms of Henoch-Schönlein purpura, although most recurrent episodes are less severe than the initial episode. However, recurrent episodes of Henoch-Schönlein purpura can last up to a year after the initial diagnosis.

Which is the most serious complication of Henoch Schonlein purpura?

Kidney damage. The most serious complication of Henoch-Schonlein purpura is kidney damage. This risk is greater in adults with the condition than in children. Occasionally the damage is severe enough that dialysis or a kidney transplant may be needed.

What kind of rash is Henoch Schonlein?

Henoch-Schonlein purpura is an inflammation of the small blood vessels of the skin, joints, bowels and kidneys. When blood vessels get inflamed, they can bleed into the skin, causing a reddish-purple rash (purpura).

How to lose weight with Henoch Schonlein purpura?

Take regular exercise. People with HSP lose a lot of muscle strength during illness. Ask for advice about sensible regular exercise. Eat well. You will probably lose some body weight with HSP in its early stages. Even if you have a weight problem, this weight loss is usually a bad thing, because it is your muscle and not your fat that is lost.

When to use prednisone for Henoch Schonlein purpura?

The use of corticosteroids, such as prednisone, in treating or preventing complications of Henoch-Schonlein purpura is controversial. They’re most often used to treat severe gastrointestinal symptoms.

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