Is there a cure for pigmentary retinopathy?
Although there is no cure for RP, treatments are available for managing some aspects of its clinical manifestations [2]. New treatments involving gene therapy, transplantation, and implanted electrical devices, are in active development.
What causes retinal pigmentation?
What causes RP? RP is an inherited disorder that results from harmful changes in any one of more than 50 genes. These genes carry the instructions for making proteins that are needed in cells within the retina, called photoreceptors.
What is pigmentary retinal degeneration?
This is a rare syndrome consisting of a pigmentary degeneration of the retina in association with nanophthalmos. The globe is small with a thickened choroid and sclera and the macula becomes atrophic later in life. Some patients have cystic macular changes early without fluorescein leakage.
Will I go blind if I have retinitis pigmentosa?
Blindness: Retinitis pigmentosa (RP) causes vision loss that worsens over time. Some people may eventually become blind, although this is rare. Cataracts: Patients with RP often develop a type of cataract called subcapsular cataracts. When this occurs, the lens becomes cloudy and vision is impaired.
What kind of disease is pigmentary retinal degeneration?
This is a rare syndrome consisting of a pigmentary degeneration of the retina in association with nanophthalmos. The globe is small with a thickened choroid and sclera and the macula becomes atrophic later in life. Some patients have cystic macular changes early without fluorescein leakage.
How old do you have to be to have retinal pigment degeneration?
REFSUM’S DISEASE (SEE CHAPTER 79 ). This demyelinating polyneuropathy and associated pigmentary retinal degeneration, characterized by night blindness, is an autosomal recessive disorder that usually presents during childhood. More than 40% of these children become symptomatic by age 10 years, and the remainder by age 20. 227,440
How is clumped pigmentary retinal degeneration similar to Rp?
Clumped pigmentary retinal degeneration (CPRD) also has similar symptoms to typical RP but has a distinct fundus appearance consisting of large, clumped pigment deposits in the periphery, instead of the pigment deposits with a bone-spicule type found in RP ( Figure 7 ).
What are the ocular features of retinal degeneration?
Nanophthalmos with Retinopathy. Ocular Features: This is a rare syndrome consisting of a pigmentary degeneration of the retina in association with nanophthalmos. The globe is small with a thickened choroid and sclera and the macula becomes atrophic later in life. Some patients have cystic macular changes early without fluorescein leakage.
