What is a large cell Acanthoma?
The large cell acanthoma presents as a slightly scaly tan macule on photodamaged skin. Clinically, it may be difficult to differentiate from a lentigo senilis, pigmented actinic keratosis, or a flat and pigmented seborrheic keratosis. We have studied 19 cases of large cell acanthoma.
What is squamous acanthoma?
An acanthoma is a skin neoplasm composed of squamous or epidermal cells. It is located in the prickle cell layer.
Is squamous acanthoma cancerous?
The exact cause of acanthoma is not known; it is sometimes called a benign tumor , and sometimes described as the result of inflammation. Acanthomas are not considered dangerous and do not require treatment, but they may be removed for cosmetic reasons or to relieve any associated symptoms.
What does a large cell acanthoma look like?
The large cell acanthoma presents as a slightly scaly tan macule on photodamaged skin. Clinically, it may be difficult to differentiate from a lentigo senilis, pigmented actinic keratosis, or a flat and pigmented seborrheic keratosis.
When to see a dermatologist for large cell acanthoma?
Therefore, a patient who has an LCA is likely to be at risk for other conditions known to develop in areas of actinic damage including actinic keratoses and skin cancer. Patients should have regular full body skin examinations by a dermatologist and should be counseled on photoprotection and the use of sunscreen.
What are the side effects of cryotherapy for acanthoma?
Should portions of the lesion remain, cryotherapy is a non-invasive treatment modality that is easily employed. Lesions treated with cryotherapy usually resolve within a week. Side effects of cryotherapy may include a scar, hypo- or hyperpigmentation. Alternative treatment includes a shave excision.
What to do after a large cell acanthoma biopsy?
Treatment of the remaining lesion after biopsy consists of cryotherapy with liquid nitrogen and may be initiated for cosmetic purposes. No therapy is another option. A definitive diagnosis of LCA will likely require pathologic evaluation. Therefore, if the entire lesion is biopsied, further treatment will not be required.
