Where does Uncoating of the viral nucleic acid occur?
Replication. Rhinovirus replication is initiated by attachment to the cell via the appropriate receptor. This attachment triggers viral uncoating with delivery of the viral genome to the cytosol of the host cell.
What is Uncoating in virus?
Virus genomes are condensed and packaged inside stable proteinaceous capsids that serve to protect them during transit from one cell or host organism, to the next. During virus entry, capsid shells are primed and disassembled in a complex, tightly-regulated, multi-step process termed uncoating.
What nucleic acids are in viruses?
Most viruses have either RNA or DNA as their genetic material. The nucleic acid may be single- or double-stranded.
What happens to the viral nucleic acid after it is injected into the host cell?
Once inside the cell, the viral capsid is degraded and the viral nucleic acid is released, which then becomes available for replication and transcription.
Where do viruses disassemble?
DISASSEMBLY AT THE PLASMA MEMBRANE AND IN ENDOSOMES. Some enveloped viruses, nonenveloped viruses, and toxins undergo disassembly on the plasma membrane or within an endosomal compartment of the host cell.
What is lacking in a virus?
Without a host cell, viruses cannot carry out their life-sustaining functions or reproduce. They cannot synthesize proteins, because they lack ribosomes and must use the ribosomes of their host cells to translate viral messenger RNA into viral proteins.
What part of a human cell does a virus use to replicate?
Most DNA viruses assemble in the nucleus; most RNA viruses develop solely in cytoplasm. Viral populations do not grow through cell division, because they are acellular. Instead, they hijack the machinery and metabolism of a host cell to produce multiple copies of themselves, and they assemble inside the cell.
