Which antibiotics can cause thrombocytopenia?
Medicines Known to Cause DITP
| Medicine Classification | Examples of Implicated Medicines |
|---|---|
| Antibiotics | Cephalosporins, linezolid, penicillins, sulphonamides, trimethoprim, vancomycin |
| Antimalarials | Quinine |
| Antimycobacterials | Ethambutol, rifampicin |
| Antiepileptics | Carbamazepine, phenytoin, sodium valproate |
Which antithrombotic drug is most likely to cause thrombocytopenia?
Glycoprotein IIb/IIIa receptor antagonists, a class of antithrombotic drugs, are a common cause of DIT and can induce life-threatening thrombocytopenia.
What is the most common drug-induced thrombocytopenia in hospitalized patients?
A systematic review of individual patient data found that the most commonly reported drugs with a definite or probable causal relation to thrombocytopenia were quinine, quinidine, trimethoprim/sulfamethoxazole, vancomycin, penicillin, rifampin, carbamazepine, ceftriaxone, ibuprofen, mirtazapine, oxaliplatin, and …
Can omeprazole cause thrombocytopenia?
Previous case reports have shown similar effects of PPI-induced thrombocytopenia for several types of PPI (e.g., pantoprazole, lansoprazole, and omeprazole). In all cases, platelet count dropped the very next day after starting PPI. The first case of pantoprazole-induced thrombocytopenia was reported by Watson et al.
Can colchicine cause thrombocytopenia?
Therapeutic doses of colchicine have reportedly correlated with myelosuppression, leukopenia, granulocytopenia, thrombocytopenia, pancytopenia, and aplastic anemia. Also, colchicine may worsen these types of blood dyscrasias.
What is drug-induced thrombocytopenia purpura?
Drug-induced thrombocytopenic purpura is a skin condition result from a low platelet count due to drug-induced anti-platelet antibodies caused by drugs such as heparin, sulfonamines, digoxin, quinine, and quinidine.
What herbs can cause thrombocytopenia?
The substances with definite evidence of causal association were milk, cranberry juice, Jui (a Chinese herbal tea with two cases reported), Lupinus termis (a North African bean), and tahini (pulped sesame seeds).
Does drug induced thrombocytopenia go away?
This predicts that thrombocytopenia will begin to resolve within several days of discontinuing the drug and its clearance from the circulation, and also explains why patients may have a high titer of drug-dependent anti-platelet antibodies for many years with no problems—until drug exposure occurs again.
Can beta blockers cause low platelets?
β-blockers are associated with decreased leucocyte-platelet aggregate formation and lower residual platelet reactivity to adenosine diphosphate after angioplasty and stenting.
Can ranitidine lower platelets?
Ranitidine is able to cause thrombocytopenia by an idiosyncratic reaction associated with an increase in platelet-induced immunoglobulins and its later clearance by the phagocytic system.
