Is whole genome sequencing ethical?
whole genome sequencing. Much has been written about ethical issues related to genetics. In fact, when the Human Genome Project was initiated in 1990, a component of the project was a focus on ethical, legal, and social implications of genomics. In the 1990s, whole genome sequencing (WGS) was not available.
Which of the following ethical considerations are most relevant to whole genome sequencing?
We identify three major ethical considerations that have been implicated in whole-genome research: the return of research results to participants; the obligations, if any, that are owed to participants’ relatives; and the future use of samples and data taken for whole-genome sequencing.
What ethical issues arise from personal genomics?
Genomics researchers collect human genetic material, including DNA and cells, from a large number of individuals and carry out “personal genome analysis”; as a result, new types of ethical, legal, and social issues (ELSI) have arisen, including issues such as informed consent procedures, data sharing, protection of …
What are the ethical implications of genome research?
When the genomic data are publicly accessible, there is a risk of discrimination during enrollment for a job or obtaining health insurance. Individuals could be denied a job or an insurance policy based on the genetic information which suggests the risk of susceptibility to any chronic disease or cancer.
Why is genome sequencing unethical?
Medical sequencing raises ethical issues for both individuals and populations, including data release and identifiability, adequacy of consent, reporting research results, stereotyping and stigmatization, inclusion and differential benefit and culturally and community-specific concerns.
What are some ethical issues with sequencing?
Who should have access to your personal genetic information?
A clinical geneticist believes that if anyone is to own genetic information, it has to be all those who have inherited it and, more importantly, it must be available to all those who might be at risk. The question, she says, is how to balance a right to privacy with disclosing risks to others.
What are 3 ethical issues with the Human genome Project?
The original issues identified in the ELSI program announcement were: questions of fairness in the use of genetic information; the impact of genetic information on individuals; privacy and confidentiality of genetic information; the impact of the HGP on genetic counseling; the impact of genetic information on …
What are 3 key results of the Human genome Project?
These “bonus” accomplishments include: an advanced draft of the mouse genome sequence, published in December 2002; an initial draft of the rat genome sequence, produced in November 2002; the identification of more than 3 million human genetic variations, called single nucleotide polymorphisms (SNPs); and the generation …
Are there any ethical issues with whole genome sequencing?
WGS raises new and different ethical issues. To see why and how this is so, it is important to understand the ethical issues that arose from the use of these other forms of genetic testing. Newborn screening is an unusual form of clinical testing. In most states, it is mandated and done without parental consent.
When was the Human Genome Project first started?
In fact, when the Human Genome Project was initiated in 1990, a component of the project was a focus on ethical, legal, and social implications of genomics. In the 1990s, whole genome sequencing (WGS) was not available.
Are there any concerns about the Human Genome Project?
Critics express several concerns about the Human Genome Project (HGP), and most involve the extent of the project or its funding. Original proposals for the project emphasized sequencing the entire human genome.
Why is there no definitive human genome sequence?
Because of the genetic variation between individuals, there never will be one definitive human sequence. The lack of a definitive sequence creates uncertainty about the appropriate definition of “normal,” which in turn makes the discussion of public policy issues difficult.
