What happens when Hy antigen is present?
H-Y antigen is defined as a male histocompatibility antigen that causes rejection of male skin grafts by female recipients of the same inbred strain of rodents.
Do males have Y chromosomes?
Each person normally has one pair of sex chromosomes in each cell. The Y chromosome is present in males, who have one X and one Y chromosome, while females have two X chromosomes. Identifying genes on each chromosome is an active area of genetic research.
What produces the HY antigen?
H-Y antigen is a male tissue specific antigen. Originally thought to trigger the formation of testes (via loci, an autosomal gene that generates the antigen and one that generates the receptor) it is now known that it does not trigger the formation of testes but may be activated by the formation of testes.
What does the H antigen do?
The Hh blood group contains one antigen, the H antigen, which is found on virtually all RBCs and is the building block for the production of the antigens within the ABO blood group. (A transfusion of “normal” group O blood can trigger a severe transfusion reaction.)
Where is the SRY protein produced?
Y chromosome
The Sry gene, located on the short branch of the Y chromosome, initiates male embryonic development in the XY sex determination system. The Sry gene follows the central dogma of molecular biology; the DNA encoding the gene is transcribed into messenger RNA, which then produces a single Sry protein.
Which blood type has the most H antigens?
blood type O
Therefore, the H antigen is present in the highest amounts in blood type O and in the least amounts in blood type AB. Two regions of the genome encode two enzymes with very similar substrate specificities—the H locus (FUT1) and the Se locus (FUT2).
Can a human have YY chromosomes?
Males with XYY syndrome have 47 chromosomes because of the extra Y chromosome. This condition is also sometimes called Jacob’s syndrome, XYY karyotype, or YY syndrome. According to the National Institutes of Health, XYY syndrome occurs in 1 out of every 1,000 boys.
