What is non Keratinizing nasopharyngeal carcinoma?
What is non-keratinizing squamous cell carcinoma of the nasopharynx? Non-keratinizing squamous cell carcinoma is a type of cancer that starts from the tissue at the back of the nose and throat. This part of the body is called the nasopharynx.
What is the best treatment for nasopharyngeal carcinoma?
The main treatment for NPC is radiation therapy. It is often given in combination with chemotherapy. This approach may be called concomitant chemoradiotherapy. Surgery for NPC is occasionally used, mainly to remove lymph nodes after chemoradiotherapy or to treat NPC that has come back after initial treatment.
How does EBV cause nasopharyngeal cancer?
Scientists are still researching how EBV leads to nasopharyngeal cancer, but it may be related to genetic material (DNA) from the virus affecting the DNA in the cells of the nasopharynx. The change in DNA causes cells to grow and divide abnormally, causing cancer.
What is metastatic nasopharyngeal carcinoma?
Most people with nasopharyngeal carcinoma have regional metastases. That means cancer cells from the initial tumor have migrated to nearby areas, such as lymph nodes in the neck. Cancer cells that spread to other areas of the body (distant metastases) most commonly travel to the bones, lungs and liver.
Can a nasopharyngeal mass be benign?
Benign nasopharyngeal tumors. Benign nasopharyngeal tumors are fairly rare and tend to develop in children and young adults. These tumors do not spread to other parts of the body and are usually not life-threatening.
What is a nasopharyngeal mass?
A nasopharyngeal tumor is a growth that forms in the nasopharynx, or the uppermost portion of the throat that is found behind the nasal cavity. The nasopharynx serves as a passageway for air from the nose to the throat and eventually to the lungs. A tumor in the nasopharynx may be either benign or malignant.
How many chemo treatments are needed for nasopharyngeal?
You usually have 3 cycles of chemotherapy before starting chemoradiotherapy. You usually have up to 6 cycles of cisplatin and gemcitabine for nasopharyngeal cancer that has spread to other parts of the body. Other chemotherapy drugs that doctors may use include: fluorouracil (5FU) and cisplatin.
Are nasopharyngeal tumors cancerous?
Nasopharyngeal cancer is a rare type of cancer that affects the part of the throat connecting the back of the nose to the back of the mouth (the pharynx).
What type of cancer does Epstein Barr virus cause?
EBV infection increases a person’s risk of getting nasopharyngeal cancer (cancer of the area in the back of the nose) and certain types of fast-growing lymphomas such as Burkitt lymphoma. It may also be linked to Hodgkin lymphoma and some cases of stomach cancer.
What is stage 4 nasopharyngeal carcinoma?
Stage IV nasopharyngeal cancer is divided into stages IVA and IVB. In stage IVA, (1) cancer has spread to the brain, the cranial nerves, the hypopharynx, the salivary gland in the front of the ear, the bone around the eye, and/or the soft tissues of the jaw.
What is a common site of metastasis for nasopharyngeal carcinoma?
The incidence of bone metastasis is approximately 64%-67%, and bone is the most common site of metastases in NPC. In addition, because the nasopharynx is adjacent to a rich lymphatic network, poorly differentiated and undifferentiated NPCs are more likely to metastasize than other head and neck squamous cancers.
What is nasopharynx carcinoma?
Nasopharyngeal carcinoma (also known as NPC) is a rare tumor of the head and neck which originates in the nasopharynx. The nasopharynx is located at the very back of the nose near the Eustachian tubes (Figure).
What does it mean to have cancer of the nasopharynx?
Nasopharyngeal cancer (staging) Nasopharyngeal cancer staging refers to TNM staging of malignant tumors of the nasopharynx. The vast majority of applicable tumors are nasopharyngeal carcinomas, but other epithelial malignancies of the nasopharynx are included, such as minor salivary gland tumors. The following article reflects
What kind of treatment is used for nasopharyngeal carcinoma?
Treatment for nasopharyngeal carcinoma usually begins with radiation therapy or a combination of radiation and chemotherapy. Radiation therapy uses high-powered energy beams, such as X-rays or protons, to kill cancer cells.
What are the symptoms of nasopharyngeal carcinoma ( NPC )?
Additional symptoms of NPC include facial pain or numbness, blurred or double vision, trouble opening the mouth, or recurring ear infections. If the ear infection does not present with an upper respiratory tract infection, then an examination should be done on the nasopharynx.
What do you mean by staging of nasopharyngeal cancer?
Nasopharyngeal cancer staging refers to TNM staging of malignant tumors of the nasopharynx. The vast majority of applicable tumors are nasopharyngeal carcinomas, but other epithelial malignancies of the nasopharynx are included, such as minor salivary gland tumors.