What is prolixin used to treat?
Fluphenazine is a medication that treats schizophrenia. It is also known as a first generation antipsychotic (FGA) or typical antipsychotic. Fluphenazine rebalances dopamine to improve thinking, mood, and behavior.
Why was Modecate discontinued?
BMS have notified the end of production of Modecate Injection due to the unpredictability of supply of fluphenazine decanoate, the active pharmaceutical ingredient (API), from the third party manufacturer, Fine Chemicals of South Africa. There are no other manufacturers of API worldwide.
Is Modecate still available?
Fluphenazine decanoate 25mg/1ml and 100mg/1ml solutions for injection ampoules (Modecate and Modecate Concentrate) manufactured by Sanofi, have been discontinued for some time and stock of any remaining batches will now have expired.
What is FD injection?
Long-acting, or ‘depot’, injections are used once your symptoms have been eased by taking tablets. The injection slowly releases fluphenazine into your body and is given every 2-5 weeks. The main advantage of a depot injection is that you do not have to remember to take tablets every day.
How long does it take prolixin to work?
It may take 1-3 days to notice an effect from this drug, and up to 4 days to experience the full effect. For severe agitation or other symptoms, use a short-acting medication as directed by your doctor.
Does prolixin cause weight gain?
Side effects include: Extrapyramidal reactions (e.g., pseudo-parkinsonism, dystonia, dyskinesia, akathisia, oculogyric crises, opisthotonos, hyperreflexia), drowsiness, lethargy, weight gain.
Is prolixin still used today?
What Is Prolixin? Prolixin (fluphenazine) is a phenothiazine, also called a neuroleptic, used to treat symptoms of a certain type of mental/mood condition (schizophrenia). The brand name Prolixin is discontinued and this medication is available in generic form only.
Does prolixin cause seizures?
US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: loss of consciousness, seizures, fast/irregular heartbeat, or slow/shallow breathing. Do not share this medication with others.
When was Modecate discontinued?
Discontinuation report MODECATE CONCENTRATE
| Report ID | 42850 |
|---|---|
| Actual discontinuation date | 2018-12-28 |
| Remaining supply date | 2018-12-28 |
| Discontinuation status | Discontinued |
| Discontinuation decision reversal | No |
How long does fluphenazine stay in your system?
Fluphenazine (decanoate) has a half‐life of 6.8 to 9.6 days following IM administration (Drugs.com).
What is the side effect of fluphenazine?
Side effects from fluphenazine are common: insomnia. nightmares. dry mouth. skin more sensitive to sunlight than usual.
Where do you inject prolixin?
Deltoid or gluteal injections are both possible; the site can be chosen based on patient preference and body habitus. Alternate sites and use 1-inch needle for deltoid, 2-inch needle for gluteal injection. Give by deep intramuscular injection and use the Z-track technique to avoid leakage.
How old do you have to be to take prolixin decanoate?
Fluphenazine decanoate is not intended for use in children under 12 years of age. Prolixin Decanoate is contraindicated in patients who have shown hypersensitivity to fluphenazine; cross-sensitivity to phenothiazine derivatives may occur.
How long does it take for prolixin decanoate to take effect?
Prolixin Decanoate Dosage and Administration. For most patients, a dose of 12.5 to 25 mg (0.5 to 1 mL) may be given to initiate therapy. The onset of action generally appears between 24 and 72 hours after injection and the effects of the drug on psychotic symptoms becomes significant within 48 to 96 hours.
Where to find medical information for prolixin decanoate injection?
Find patient medical information for Prolixin Decanoate injection on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Skip to main content
Who are poor risk patients for prolixin decanoate?
“Poor risk” patients (those with known hypersensitivity to phenothiazines, or with disorders that predispose to undue reactions): Therapy may be initiated cautiously with oral or parenteral fluphenazine hydrochloride (see package inserts accompanying these products for complete information).
