What are the symptoms of drug-induced lupus?

What are the symptoms of drug-induced lupus?

The symptoms of drug-induced lupus

  • muscle and joint pain sometimes with swelling.
  • flu-like symptoms of fatigue and fever.
  • serositis (inflammation around the lungs or heart that causes pain or discomfort)
  • certain laboratory test abnormalities.

Which drugs cause drug-induced lupus?

The most common medicines known to cause drug-induced lupus erythematosus are:

  • Isoniazid.
  • Hydralazine.
  • Procainamide.
  • Tumor-necrosis factor (TNF) alpha inhibitors (such as etanercept, infliximab and adalimumab)
  • Minocycline.
  • Quinidine.

How is drug-induced lupus caused?

Drug-induced lupus is an autoimmune disorder caused by a reaction to certain medications. The two drugs most often associated with drug-induced lupus are procainamide, which is used to treat irregular heart rhythms, and hydralazine, a high blood pressure medicine.

What are the three forms of drug-induced lupus erythematosus?

As in idiopathic or usual-type lupus erythematosus (LE), there are three categories recognised: Drug-induced systemic LE (SLE) Drug-induced subacute cutaneous LE (SCLE) Drug-induced chronic cutaneous LE (CLE).

What drugs can cause a positive ANA?

Positive antinuclear antibody (ANA) test result; usually antihistone antibodies….Medications reported to have a definite relationship to DILE, based on controlled studies, include the following2:

  • Sulfadiazine.
  • Hydralazine.
  • Procainamide.
  • Isoniazid.
  • Methyldopa.
  • Quinidine.
  • Minocycline.
  • Chlorpromazine.

Can Hashimoto’s turn into lupus?

Automimmune disorders that occur with increased frequency in patients with Hashimoto’s thyroiditis include insulin-dependent diabetes mellitus, myasthenia gravis, celiac disease, pernicious anemia, vitiligo, rheumatoid arthritis, systemic lupus erythematosus, scleroderma, primary biliary cirrhosis, dermatitis …

Is drug-induced lupus rare?

Drug-induced lupus (DIL) is a rare autoimmune disease caused by a reaction to certain drugs. There are an estimated 15,000 to 30,000 cases of drug-induced lupus per year.

What drugs can cause drug induced lupus?

Here is a list of the most common drugs which act as toxic agents causing drug-induced lupus. Procainamide. Hydrazine. Chlorpromazine. Quinidine. Isoniazid. Diltiazem. Minocycline.

What are the symptoms of medication induced lupus?

Signs and symptoms of drug-induced lupus erythematosus include the following: Joint pain (arthralgia) and muscle pain (myalgia) Fatigue.

What medications cause lupus?

Medication causes: Common medications that may cause drug-induced lupus include hydralazine (Apresoline_), procainamide (Procan_, Pronestyle_), methyldopa (Aldornet_), quinidine (Quinaglute_), isoniazid (INH_), and some anti-seizure medications such as phenytoin ( Dilantin _) or carbamazepine ( Tegretol _).

Does hydralazine cause lupus like syndrome?

Long-term administration of hydralazine in large doses may cause a syndrome resembling lupus erythematosus, particularly in slow acetylators.

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