What is the action of imipramine?
Imipramine is a tricyclic antidepressant that has been used since the 1950s. Its primary mechanism of action is to inhibit the reuptake of serotonin and norepinephrine, thus elevating the levels of these neurotransmitters in the brain.
What is imipramine used for?
Imipramine is a tricyclic antidepressant used to treat symptoms of depression. Imipramine is sometimes used to treat bed-wetting in children ages 6 and older. Imipramine may also be used for purposes not listed in this medication guide.
Is imipramine a sleeping pill?
Using this medication to treat depression may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. Imipramine can help your child control nighttime bed-wetting. Imipramine belongs to a class of medications called tricyclic antidepressants.
Is imipramine safe for kids?
Do not give this medicine to a child without medical advice. Imipramine is not approved to treat depression in anyone younger than 18 years old. Imipramine should not be used to treat bed-wetting in a child younger than 6 years old.
Is imipramine more potent than desipramine?
Once again, urine desipramine concentrations were slightly higher than imipramine concentrations.
Can imipramine cause liver damage?
Imipramine is a tricyclic antidepressant that continues to be widely used in the therapy of depression. Imipramine can cause mild and transient serum enzyme elevations and is rare cause of clinically apparent acute cholestatic liver injury.
Is imipramine bad for your heart?
Imipramine caused a moderate increase in supine systolic blood pressure, and a pronounced increase in the rise in heart rate, when the subjects assumed erect position.
What is popular brand name of imipramine?
Imipramine(Tofranil) generic is an antidepressant, prescribed for depression. It is also used to treat bedwetting in children. It increases the amount of certain natural substances in the brain.
Is imipramine good for anxiety?
Physicians use tricyclic antidepressants in the treatment of panic disorder, PTSD, generalized anxiety and depression that occurs with anxiety. Of this family, imipramine has been the focus of most of the panic treatment research.
What is the most sedating tricyclic antidepressant?
All TCAs are equally effective for the treatment of depression, and the choice of a particular one is determined by side effects. The magnitude of anticholinergic and antihistaminic effects is the largest determinant. Amitriptyline and imipramine are more sedating, with more weight gain and orthostatic hypotension.
Does imipramine cause heart problems?
Among the patients with cardiovascular disease, 4 developed congestive heart failure during imipramine administration, while severe postural hypotension was observed in 10 of 41 (24.4 per cent). Two developed myocardial infarction during a hypotensive period.
Can imipramine cause psychosis?
Psychiatric: Confusional states (especially in the elderly) with hallucinations, disorientation, delusions; anxiety, restlessness, agitation; insomnia and nightmares; hypomania; exacerbation of psychosis.
What do you need to know about imipramine tablets?
Descriptions. Imipramine is used to treat depression. It belongs to a group of medicines known as tricyclic antidepressants (TCA). These medicines are thought to work by increasing the activity of a chemical called serotonin in the brain. Imipramine tablets are also used to treat enuresis (bedwetting) in children.
How does imipramine work to prevent bedwetting?
Imipramine is in a class of medications called tricyclic antidepressants. It treats depression by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. There is not enough information to explain how imipramine prevents bedwetting.
How old do you have to be to take imipramine?
talk to your doctor about the risks and benefits of taking imipramine if you are 65 years of age or older. Older adults should not usually take imipramine because it is not as safe and effective as other medications that can be used to treat the same condition.
Is it safe to take imipramine for bulimia nervosa?
According to World Federation of Societies of Biological Psychiatry guidelines for the pharmacological treatment of eating disorders, imipramine is effective and recommended in the management of bulimia nervosa [WFSBP [Aigner 2011]].
