What are the molecular classes of breast cancer?
The current molecular classification divides breast cancer into five groups as luminal A, luminal B, HER-2, basal and normal breast like. Further grouping of these subgroups seem possible and necessary.
What are the limitations of breast cancer?
According to a new study published online in “The Journal of the National Cancer Institute,” breast cancer survivors with functional limitations – an inability to perform normal daily activities – caused by the disease or its treatment are more likely to die because of overall poorer health.
What is the molecular cause of breast cancer?
Acquired DNA mutations take place over time and are only in the breast cancer cells. Mutated DNA can lead to mutated genes. Some genes control when our cells grow, divide into new cells, and die. Changes in these genes can cause the cells to lose normal control and are linked to cancer.
Why is breast cancer common in the Philippines?
Smoking, excessive drinking, unhealthy diet, and lack of exercise are among the major factors that cause non-communicable diseases such as breast cancer. 26 females out of 100 females and 1 male for every 105 males may be diagnosed with breast cancer in the Philippines.
What are the two major subtypes of breast cancer?
Invasive ductal carcinoma and lobular carcinoma may be categorized as any of the four molecular subtypes. About 85 percent of breast cancers are ductal carcinomas, while 11.4 percent are lobular carcinomas, according to a study published in the Annals of Medicine and Surgery.
What is the most aggressive subtype of breast cancer?
Triple negative breast cancer (TNBC) is a more aggressive subtype of breast cancer and is characteristic of the absence of the expressions of estrogen receptor, progesterone receptor, and human epithelial growth factor receptor 2 in breast tumor tissues.
What are the disadvantages of breast cancer screening?
Overall, screening mammograms do not find about 1 in 5 breast cancers. Women with dense breasts are more likely to get false-negative results. False-negative mammograms can give women a false sense of security, thinking that they don’t have breast cancer when in fact they do.
What is the most common cancer in the Philippines?
Cancer is the second leading cause of death among Filipinos. The most common cancers are breast, lung, colorectal, liver, and prostate. Among Filipino women, there are still high rates of cervical cancer. Only breast cancer is more common.
What ranked as top 1 cancer in the Philippines in male and female?
In Cebu, liver cancer is the leading malignancy site for males as well as for both sexes together, followed by cancers of the lung, colon-rectum, leukemia and stomach. In females, breast cancer, is the most important malignancy, followed by cervix, lung and colon-rectum.
What are the molecular subtypes of breast cancer?
HER2-enriched breast cancer is hormone-receptor negative (estrogen-receptor and progesterone-receptor negative) and HER2 positive.
What’s the difference between luminal A and B breast cancer?
Luminal A cancers are low-grade, tend to grow slowly and have the best prognosis. Luminal B breast cancer is hormone-receptor positive (estrogen-receptor and/or progesterone-receptor positive), and either HER2 positive or HER2 negative with high levels of Ki-67.
Which is the best type of breast cancer?
Luminal A breast cancer is hormone-receptor positive (estrogen-receptor and/or progesterone-receptor positive), HER2 negative, and has low levels of the protein Ki-67, which helps control how fast cancer cells grow. Luminal A cancers are low-grade, tend to grow slowly and have the best prognosis.
Is there such a thing as normal like breast cancer?
Normal-like breast cancer is similar to luminal A disease: hormone-receptor positive (estrogen-receptor and/or progesterone-receptor positive), HER2 negative, and has low levels of the protein Ki-67, which helps control how fast cancer cells grow.
