What is function of Paneth cells?

What is function of Paneth cells?

Paneth cells are highly specialized secretory epithelial cells located in the small intestinal crypts of Lieberkühn. The dense granules produced by Paneth cells contain an abundance of antimicrobial peptides and immunomodulating proteins that function to regulate the composition of the intestinal flora.

What does Paneth cell secrete?

Paneth cells are specialized intestinal epithelial cells that secrete abundant antimicrobial proteins, including lysozyme, and thus disrupting Paneth cell secretion can lead to inflammatory disease (2–4).

What is the main function of an Enterocyte?

A glycocalyx surface coat contains digestive enzymes. Microvilli on the apical surface increase its surface area. This facilitates transport of numerous small molecules into the enterocyte from the intestinal lumen….

Enterocyte
Shape simple columnar
Function Epithelial cells
Identifiers
Latin enterocytus

Where is Paneth cell located?

small intestinal crypts
Paneth cells are highly specialized secretory epithelial cells located in the small intestinal crypts of Lieberkühn. The dense granules produced by Paneth cells contain an abundance of antimicrobial peptides and immunomodulating proteins that function to regulate the composition of the intestinal flora.

How do enterocytes absorb?

Enterocytes in the small intestine absorb large amounts of sodium ion from the lumen, both by cotransport with organic nutrients and by exchange with protons.

What are enterocytes covered with?

The inner wall of the small intestine is covered by numerous folds of mucous membrane called plicae circulares. The surface of these folds contains tiny projections called villi and microvilli, which further increase the total area for absorption.

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