What causes reactive perforating collagenosis?
The underlying cause of reactive perforating collagenosis is unknown, but an abnormal response to superficial trauma (eg, scratching) may be involved. Papules have been reported following scratches, acne spots, insect bites, and scabies.
What does reactive perforating collagenosis mean?
Reactive perforating collagenosis is a rare skin disorder characterized by the transepidermal elimination of altered collagen through the epidermis. The 2 distinct forms of are an inherited form that manifests in childhood and an acquired sporadic form that occurs in adulthood.
Is perforating collagenosis curable?
Treatment of reactive perforating collagenosis lesions is often unsatisfactory; in many cases, the lesions are self-healing, but usually are recurrent.
What causes acquired perforating dermatosis?
Acquired perforating dermatosis is a chronic disease, usually associated with diabetes mellitus or renal failure or both. In patients receiving dialysis, acquired perforating dermatosis occurs in about 10% of patients. It is also rarely associated with liver disease, malignant disease, hypothyroidism and HIV.
What is Elastosis Perforans Serpiginosa?
Elastosis perforans serpiginosa is a rare skin disease characterized by transepidermal elimination of abnormal elastic fibers. This condition classically presents as small papules arranged in serpiginous or annular patterns on the neck, face, arms, or other flexural areas.
What is serpis disease?
Elastosis perforans serpiginosa (EPS) is a rare skin disease in which abnormal elastic tissue fibers, other connective tissue elements, and cellular debris are expelled from the papillary dermis through the epidermis (transepithelial elimination).
What kind of skin disease is reactive perforating collagenosis?
Reactive perforating collagenosis (RPC), a subtype of perforating dermatoses (PD), is a rare skin disease, characterized by transepidermal elimination of altered dermal collagen. [1] There are two types of RPC, acquired RPC (ARPC) and inherited RPC (IRPC). [2]
How to treat reactive perforating collagenosis ( dovemed )?
However, for severe cases, the treatment strategies that may be adopted include: 1 Vitamin A therapy. 2 Antibiotics such as doxycycline. 3 Phototherapy. 4 Moisturizing creams and antihistamines to help with itching. 5 For mild skin conditions, self-care measures are recommended, such as washing with mild… 6 (more items)
How to treat reactive perforating dermatoses ( RPC )?
Co-administration of two or more agents for dermatologic interventions and treatment for associated diseases may help to improve skin symptoms. Reactive perforating collagenosis (RPC), a subtype of perforating dermatoses (PD), is a rare skin disease, characterized by transepidermal elimination of altered dermal collagen. [1]
