What is a RPR titer 1 1?
A confirmed case of syphilis was defined as an RPR titer ≥1:1 with a positive TPHA result. All positive results, including syphilis diagnoses, were communicated with patients and attending clinicians in order to provide appropriate therapy.
What does a 1 to 1 titer mean?
For example, a titer increase from 1:1 to 1:4 would indicate a re-infection. Treponemal Test. (Immunoassay) Reactive.
What does RPR 1/16 mean?
Syphilis antibodies should be lower following treatment. For example, if the RPR was initially reported as 1:256, a value of 1:16 after treatment would indicate a lower level of antibody. If the titer remains the same or rises, the affected person may have a persistent infection or was reinfected.
What testing methods are used to detect syphilis?
Direct diagnosis Dark-field microscopy Direct fluorescent antibody test for Treponema pallidum Nucleic acid amplification (PCR based) methods. It is based on serological tests for the detection of antibodies. Serological testing is the mainstay in the laboratory diagnosis and follow-up of syphilis.
How accurate is the test for syphilis?
Syphilis. The most common syphilis test is designed to detect the presence of antibodies in the blood. Doctors cannot always control the outcome of this test, so science has been struggling for years to introduce a better diagnostic solution. According to one study, the accuracy of this test should be around 85%.
What can cause a false positive test for syphilis?
A false-positive test for syphilis means that the test is abnormal (or positive) despite the absence of syphilis. Another test (called the FTA) can rule out or confirm syphilis if the first screening test (called the RPR) is positive. The most common reason for a false-positive is that a person produces antibodies that “fool” the syphilis test.
Will I always test positive for syphilis?
A positive FTA-ABS test result (for the most part) indicates that the patient has (at some point) been infected with syphilis. However, patients who have had syphilis will always test positive using FTA-ABS — even when the disease has been successfully treated.
