What are the side effect of tuberculosis drugs?
Some of the potential side effects to be aware of when taking TB medication are:
- itchy skin.
- skin rashes, bruising or yellow skin.
- upset stomach, nausea, vomiting, diarrhoea or loss of appetite.
- lack of feeling or tingling in the hands or feet.
- changes in your eyesight, particularly changes in red or green colour vision.
How do anti tuberculosis drugs work?
TB drugs can kill all the TB bacteria in a person’s body. This means that the person is then cured of TB. But TB bacteria die very slowly, and so the drugs have to be taken for several months. Even when a patient starts to feel better they can still have bacteria alive in their body.
What are the side effects of latent TB medicine?
Is latent TB treatment safe?
- orange staining to tears, saliva, urine and other bodily fluids – this is not harmful but it may stain contact lenses.
- flu-like symptoms.
- menstrual disturbances.
- reduced effectiveness of hormonal contraceptives.
- tingling or numbness.
- rashes and itchiness.
- sickness or diarrhoea.
What are the mechanisms of action for tuberculosis?
Tuberculosis drugs target various aspects of Mycobacterium tuberculosis biology, including inhibition of cell wall synthesis, protein synthesis, or nucleic acid synthesis. For some drugs, the mechanisms of action have not been fully identified. Nitroimidazoles, SQ-109,, Meropenem, and Benzothiazinones act on cell wall synthesis.
Are there any second line drugs for tuberculosis?
Second-line drugs may have more side effects, the treatment may last much longer, and the cost may be up to 100 times more than first-line therapy. MDR TB strains can also grow resistant to second-line drugs, further complicating treatment. Bedaquiline and Delamanid are new drugs.
What kind of drugs are used for MDR TB?
MDR TB occurs when a Mycobacterium tuberculosis strain is resistant to isoniazid and rifampin, two of the most powerful first-line drugs. To cure MDR TB, healthcare providers must turn to a combination of second-line drugs, several of which are shown here.
What are the side effects of antituberculosis drugs?
Hematological reactions, e.g., thrombocytopenia, agranulocytosis, eosinophilia, and anemia) may occur. Reversible vasculitis may occur and arthritic symptoms at various joints may be observed. Effects include dry mouth and epigastric distress; methemoglobinemia, tinnitus, and urinary retention.
